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c/tapering·submitted 16 days ago by u/priya_guerrero

[Discussion] restarting is not failing and we should say that louder

Discussionbranch of 4 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking tapering against ApoB for 35 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one assay,…

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4 comments, started 14 days ago
u/zeynep_zielinski84 points·14 days ago

This is correct. Discontinuation data is real.

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u/viktor_laurent70 points·14 days ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/priya_guerreroOP35 points·14 days ago

STEP 1 and SURMOUNT-4 discontinuation arms show regain

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u/micro_bump_mick52 points·14 days ago

appetite return timelines vary appetite return

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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