GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of [Meta] proposal — a flair for discontinuation posts — 7 comments in the full submission. View in context.
0
c/tapering·submitted 1 months ago by u/lina_adebayo

[Meta] proposal — a flair for discontinuation posts

Trial Databranch of 5 comments

Right, the regain question again, but with numbers this time. I have 21 data points over 8 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am describing…

Read the full submission and all 7 comments →

This branch

5 comments, started 1 months ago
u/malin_petrescu3 points·1 months ago

cite the discontinuation data rather than guessing regain rates

replysharereportpermalink
u/katrin_diallo-10 points·1 months ago

cite the discontinuation data rather than guessing regain rates

Adding to this: interval stretching is doing more work than the comment implies.

replysharereportpermalink
u/nabila_bakken1 point·1 months ago

cite the discontinuation data rather than guessing regain rates Adding to this: interval stretching is doing more work than the comment implies.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

replysharereportpermalink
u/vikram_asante1 point·1 months ago

This is correct. Discontinuation data is real.

replysharereportpermalink
u/arne_restrepo1 point·1 months ago

regain on taper is expected, plan for it

replysharereportpermalink

← back to the whole thread

About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

20kmembers
62submissions
Jun 2024created
submissions / month, last year
Sponsored

Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

janoshik.comSponsored

GL Biochem (Shanghai)

Custom peptides and amino acids direct from the manufacturer since 1998. ISO 9001 / cGMP. Batch COA every order.

glbiochem.net
More in c/tapering
c/tapering rules
  1. Cite the discontinuation data rather than guessing at regain rates.
  2. No shaming people who restart.
  3. Say how long you were on and at what dose before you tapered.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/taper_off_tabithau/maintenance_mode_maxu/skip_week_sceptic
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →