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c/tapering·posted 2 months ago by u/liv_kuipers

[Question] New Zealand — has anyone got a straight answer on appetite return

Question

regain. That is the whole post, but I will justify it.

Everything else people worry about in c/coa is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort regain out first, and almost nobody does.

I say this having got it wrong for 9 months. My triglycerides was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

1,428 up / 1,225 down54% upvoted14 commentsid 1e241j27 May 2026

14 comments

6 in this archive, depth 3

best — the order this archive was captured in

u/zeynep_ndiaye17 points·2 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/ismael_eriksen5 points·2 months ago

interval stretching versus dose reduction

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u/adaeze_brandt16 points·2 months ago
saved. thank you.
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u/liv_kuipersOP7 points·2 months ago

no shaming people who restart

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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