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c/survodutide·submitted 1 months ago by u/tuva_kirchner

[Question] how do you actually verify glucagon

Questionbranch of 9 comments

Quick one. Canada here. MASH works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 24 weeks and cost roughly what I expected. The admin was worse than the cost.…

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9 comments, started 1 months ago
u/dexa_twice_yearlybody comp43 points·1 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/marisol_frisk27 points·1 months ago

the safety profile is not just tirzepatide amplified

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u/renzo_yildiz11 points·1 months ago

hepatic fat and survodutide are the story

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u/meera_sandvik14 points·1 months ago

Strongly agree. The safety story is separate.

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u/rania_salinas11 points·1 months ago

glucagon injection is a different vector than GLP-1

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u/injection_site_iris8 points·1 months ago

glucagon co-agonism has a different safety story

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u/endotoxin_elliemicro6 points·1 months ago

glucagon injection is a different vector than GLP-1

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u/chidi_demir17 points·1 months ago

This is correct. Do not generalise from tirzepatide.

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u/tuva_kirchnerOP10 points·1 months ago

glucagon injection is a different vector than GLP-1

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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