France: survodutide, and what it actually costs here
Confession thread, sort of. I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 14 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have constipation…
hepatic fat and survodutide are the story
glucagon injection is a different vector than GLP-1
Small correction: the trial was 21 weeks, not 10. Does not change your point but people will quote it.
Hepatic fat or MASH or what?
phase 24 data is interesting, phase 32 will be different
This is the "correlation is mechanism" thing again. You changed three variables at once.
glucagon injection is a different vector than GLP-1
I am going to push back on this slightly.
Yeah, glucagon co-agonism is genuinely different.