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c/survodutide·submitted 2 years ago by u/ismael_nwosu

reading survodutide threads from 2024 and half of it aged badly

Cautionbranch of 7 comments

Confession thread, sort of. I went from 1.7mg to 0.25mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 18 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have sulphur…

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7 comments, started 2 years ago
u/nadia_kjaer96 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/chidi_demir43 points·2 years ago

glucagon co-agonism has a different safety story

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u/cesar_ivaturi-27 points·2 years ago

do not generalise from tirzepatide

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u/ismael_nwosuOP39 points·2 years ago

Week 26 for me and the honest summary is: 14kg down, reflux manageable, and I have thought about food maybe four times today.

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u/incretin_ivypharmacology18 points·2 years ago

Week 26 for me and the honest summary is: 14kg down, reflux manageable, and I have thought about food maybe four times today.

Disagree on that part. 95.1% and 95.1% on the same vial is normal.

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u/certified_referenceQC13 points·2 years ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/ismael_nwosuOP23 points·2 years ago

rodent survodutide is investigation only

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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