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c/survodutide·submitted 5 months ago by u/employer_carveout

three years of hepatic fat threads, summarised so you do not have to read them

Trial Databranch of 9 comments

Been lurking in c/t2dglp1 for about 4 months and finally have something worth posting. Short version: week 44, 2.4mg, and hepatic fat is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 9 threads, and the answers split roughly down the middle. What I actually want to know is…

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9 comments, started 5 months ago
u/tired_ledger_ftw46 points·5 months ago

glucagon co-agonism has a different safety story

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u/runa_pires32 points·5 months ago

Disagree. What you are describing is consistent with MASH, not with what you concluded.

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u/thermal_mass_tom22 points·5 months ago

the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1

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u/employer_carveoutOP12 points·5 months ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/mod_cold_roommod · c/coldchain18 points·5 months ago

Not convinced. The evidence does not support that reading.

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u/cato_batista15 points·5 months ago

This is correct. Do not generalise from tirzepatide.

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u/vikram_mbeki10 points·5 months ago

not approved, descriptive posts only

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u/neha_rahimi0 points·5 months ago

not approved, descriptive posts only

Disagree on that part. 96.8% and 96.2% on the same vial is normal.

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u/isabela_nilsen14 points·5 months ago

Phase 12 or 9?

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About c/survodutide

Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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