nobody warned me about fatigue and I would have liked the warning
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking hair loss against ApoB for 39 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
Same experience. Week 50 and it simply stopped. I know that is not useful information but it is what happened.
the muscle cramps passes. i promise. not medical advice.
Went to A&E convinced it was pancreatitis. Lipase normal. It was gallstones. Get checked, do not post and wait.
Same experience. Week 72 and it simply stopped. I know that is not useful information but it is what happened.
Went to A&E convinced it was pancreatitis. Lipase normal. It was gallstones. Get checked, do not post and wait.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
hair loss is real and usually reversible when you stabilize
constipation is real, boring, and fixable
This is correct. The fatigue is horrible for three weeks and then just ends.
This is correct. The muscle cramps is horrible for three weeks and then just ends.
This is correct.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
Has anything else changed? Sleep, food, protein, anything?
Did the injection-site soreness start before or after the dose increase?
Crossposting this to c/orforglipron because the people who need it are not reading this community.
Resting heart rate up 5 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.
the food-noise thing stops around week 37 for most people
week 19 and the nausea is finally getting better
Did the early fullness start before or after the dose increase?
This is the "correlation is mechanism" thing again. You changed three variables at once.
week 71 and the muscle cramps is finally getting better
severe abdominal pain is an urgent-care question, not a forum question
Mechanistically the bit that matters is fatigue. It explains most of the early profile and a decent chunk of the outcome.
- 1Same experience. Week 72 and it simply stopped. I know that is not useful…7 comments in this branch · started by u/step_therapy_s
- 2week 19 and the nausea is finally getting better6 comments in this branch · started by u/insulin_syringe_ian