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c/sideeffects·posted 5 months ago by u/neha_rahimi

week 21 check-in — 21kg down, injection-site soreness manageable, one thing confusing me

Side Effects Receipts ×5 Slow Clap ×3

Something I noticed reading old threads that I have not seen said out loud.

The advice on constipation in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

1,361 up / 275 down83% upvoted38 commentsid 1c5pf86 Feb 2026

38 comments

14 in this archive, depth 3

best — the order this archive was captured in

u/placebo_arm_pam219 points·5 months ago·edited

Is that before or after you stabilized your constipation?

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u/constipation_clubMOD121 points·5 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/coring_the_stopper141 points·5 months ago

This is correct. The constipation is horrible for three weeks and then just ends.

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u/neha_rahimiOP76 points·5 months ago

My early fullness was worst at 1.7mg and better at 1.0mg, which makes no sense but it is real.

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u/ayesha_radich65 points·5 months ago

Same experience. Week 77 and it simply stopped. I know that is not useful information but it is what happened.

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u/vendorinvestigate_vic20 points·5 months ago

Not convinced. The evidence does not support that reading.

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u/salma_baptista17 points·5 months ago

nausea on day 2 is normal, nausea after week 37 is worth checking

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u/quiet_moderatormod21 points·5 months ago·edited

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/nabila_ogunleye46 points·5 months ago·edited

The constipation was genuinely awful for three weeks and then simply stopped. Week 23 me did not think I would make it to week 69.

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u/chidi_abubakar41 points·5 months ago

constipation is real, boring, and fixable

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u/leila_silva15 points·5 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/neha_rahimiOP21 points·5 months ago

hair loss is real and usually reversible when you stabilize

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u/tomas_lehtinen26 points·5 months ago

This is correct. The reflux is horrible for three weeks and then just ends.

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u/rania_diallo20 points·5 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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