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c/sideeffects·submitted 1 months ago by u/rafael_ostergaard

[Lab] SGN reta — VendorInvestigate came back 93.7% against a claimed 94.2%

Questionbranch of 14 comments

Posting this because I searched for it and got nothing useful. Setup: 0.5mg, week 58, injection-site soreness present but not ruining anything. I changed exactly one variable — constipation — and tracked it for 7 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else…

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14 comments, started 1 months ago
u/food_noise_gonemaintenance14 points·1 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/adaeze_batista9 points·1 months ago

the muscle cramps passes. i promise. not medical advice.

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u/long_post_larry13 points·1 months ago

hair loss is real and usually reversible when you stabilize

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u/brigade_detector5 points·1 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/leila_silva1 point·1 months ago

the food-noise thing stops around week 68 for most people

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u/iman_falk1 point·1 months ago

the food-noise thing stops around week 68 for most people

Disagree on that part. 98.7% and 98.9% on the same vial is normal.

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u/elin_lindqvist1 point·1 months ago

week 57 and the nausea is finally getting better

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u/elin_lindqvist12 points·1 months ago

Rodent data is rodent data.

Disagree on that part. 97.4% and 95.1% on the same vial is normal.

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u/karma_irrelevant3 points·1 months ago

Rodent data is rodent data.

Yes, exactly this, and it is the bit that took me 95 weeks to accept.

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u/ayesha_erdogan2 points·1 months ago

Did the constipation start before or after the dose increase?

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u/blank_injection8 points·1 months ago

sulphur burps are disgusting but not dangerous, 13 weeks and they stopped

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u/saskia_lokken6 points·1 months ago

Slight fix: the number was 97.2, not 97.4. Decimal point, but a fairly consequential one.

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u/amara_haddad2 points·1 months ago

Is that before or after you stabilized your sulphur burps?

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u/plain_titration_20241 point·1 months ago

Is that before or after you stabilized your sulphur burps?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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