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c/reconstitution·posted 2 years ago by u/tomas_kimani

[Meta] the units rule is doing its job and people should stop complaining

PSA Receipts ×9

I have had 11 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 6 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 99.0% against a claimed 98.0%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

760 up / 255 down75% upvoted25 commentsid fbktye19 Apr 2024

25 comments

19 in this archive, depth 5

best — the order this archive was captured in

u/priya_weiss127 points·2 years ago

u-100 syringe, not u-40, or your math is off by factor of 11

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u/iman_falk79 points·2 years ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/sock_puppet_spotter31 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/ahmed_rasmussen19 points·2 years ago

15mg vial, 2mL water, concentration is 15/2 — write it on the vial afterwards

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u/emil_wojcik10 points·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/gradient_goblin5 points·2 years ago

15mg vial, 2mL water, concentration is 15/2 — write it on the vial afterwards

Yes, exactly this, and it is the bit that took me 82 weeks to accept.

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u/santiago_ndiaye7 points·2 years ago

Respectfully this is a sample of one presented as a finding.

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u/karl_fischer_kev-16 points·2 years ago

the concentration on the vial in marker is the most important step

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u/quiet_reader_991 point·2 years ago

Not to be pedantic but concentration and insulin syringe are being used interchangeably and they are not interchangeable in real life.

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u/reflux_report1 point·2 years ago·edited

stopper coring on the 6th draw because you keep using the same entry point. rotate.

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u/tomas_kimaniOP1 point·2 years ago

never post a calculation as advice without stating the concentration

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u/niels_roos1 point·2 years ago·edited

Did you write the concentration on the vial?

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u/aleksi_lehtinen1 point·2 years ago

swirl, do not shake, or you are courting oxidation

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u/viktor_erdogan1 point·2 years ago·edited

bacteriostatic and sterile water are not interchangeable, do not use them that way

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u/spain_receta1 point·2 years ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/tomas_kimaniOP1 point·2 years ago

i am begging people to write down the concentration

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u/aurel_boateng47 points·2 years ago

stopper coring on the 2th draw because you keep using the same entry point. rotate.

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u/RetaAndRegret231 points·2 years ago

i am begging people to write down the concentration

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u/arto_falk46 points·2 years ago

the concentration on the vial in marker is the most important step

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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c/reconstitution rules
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