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c/reconstitution·submitted 2 years ago by u/aleksi_lehtinen

the bacteriostatic water question that gets asked weekly, answered properly

Mathbranch of 8 comments

Posting this because I searched for it and got nothing useful. Setup: 0.25mg, week 32, sulphur burps present but not ruining anything. I changed exactly one variable — concentration — and tracked it for 9 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it.…

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8 comments, started 2 years ago
u/swirl_dont_shakereconstitution36 points·2 years ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/erez_perrin42 points·2 years ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/clara_weiss11 points·2 years ago

Disagree. What you are describing is consistent with reconstitution, not with what you concluded.

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u/lurker_for_years-7 points·2 years ago

Slight fix: the number was 97.6, not 97.2. Decimal point, but a fairly consequential one.

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u/adaeze_cabrera1 point·2 years ago

Did you write the concentration on the vial?

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u/elin_ferrari1 point·2 years ago

show your working or it is unhelpful

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u/aleksi_lehtinenOP22 points·2 years ago

The single most useful thing I did was write the concentration on the vial. Stopped all the confusion after that.

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u/niels_roos6 points·2 years ago

Slight fix: the number was 98.1, not 98.0. Decimal point, but a fairly consequential one.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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