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c/reconstitution·posted 2 years ago by u/yusuf_nakamura

bacteriostatic water is the most under-discussed thing in c/sideeffects

Explainer Well Actually ×3

Right, the bacteriostatic water question again, but with numbers this time.

I have 2 data points over 18 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.

The thing I would flag for anyone new: the effect I am describing showed up at week 72, not week 26. People give up long before the interesting part.

Interested in whether this matches other people's logs or whether I am an outlier.

37 up / 56 down40% upvoted13 commentsid 1j9nxq26 Nov 2023

13 comments

13 in this archive, depth 4

best — the order this archive was captured in

u/elodie_grimaldi6 points·2 years ago

What was the vial size and how much bac water?

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u/rosa_mensah7 points·2 years ago

i am begging people to write down the concentration

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u/ruben_cabrera8 points·2 years ago

show your working or it is unhelpful

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[deleted]5 points·2 years ago

[deleted]

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u/anjali_tamm2 points·2 years ago

dead space is real and the syringe matters

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u/britta_nakamura4 points·2 years ago

swirl, do not shake, or you are courting oxidation

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u/katrin_marchetti1 point·2 years ago

I am going to push back on this slightly.

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u/rina_bergstrom3 points·2 years ago

This is correct. 2mL versus 5mL is the common mistake.

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u/lurker_for_years1 point·2 years ago

What was the vial size and how much bac water?

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u/runa_grimaldi1 point·2 years ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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u/katrin_marchetti-37 points·2 years ago

Are you using a u-100 or u-40 syringe? That changes everything.

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u/vito_beaulieu1 point·2 years ago

the concentration on the vial in marker is the most important step

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u/cesar_ivaturi1 point·2 years ago

Are you using a u-100 or u-40 syringe? That changes everything.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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