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c/reconstitution·submitted 10 months ago by u/rina_bergstrom

unpopular opinion: units is massively overrated

Explainerbranch of 9 comments

Right, the reconstitution question again, but with numbers this time. I have 22 data points over 8 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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This branch

9 comments, started 10 months ago
u/anjali_tamm702 points·10 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/andres_sorensen387 points·10 months ago

I am going to push back on this slightly.

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u/rina_bergstromOP216 points·10 months ago

Dead space ate 10 units on a low-volume draw. Tiny impact at 7.5mg, massive impact at 5mg.

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u/nabila_espinoza71 points·10 months ago·edited

Not to be pedantic but concentration and insulin syringe are being used interchangeably and they are not interchangeable in real life.

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[removed]92 points·10 months ago

[removed by moderator]

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u/priya_weiss124 points·10 months ago

Are you using a u-100 or u-40 syringe? That changes everything.

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u/georgi_adebayo866 points·10 months ago·edited

dead space is real and the syringe matters

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u/a1c_arcT2D282 points·10 months ago

Small correction: the trial was 6 weeks, not 34. Does not change your point but people will quote it.

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u/quarter_dose_queenlow and slow247 points·10 months ago

swirl, do not shake, or you are courting oxidation

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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