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c/reconstitution·submitted 1 months ago by u/a1c_arc

[Discussion] mg/mL is doing more work than we give it credit for

Discussionbranch of 5 comments

Genuinely asking, not being difficult. Everyone in c/cagrilintide repeats that concentration is important. I believe it, but I have never seen anyone show why, and when I search I get 13 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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5 comments, started 1 months ago
u/reflux_report46 points·1 months ago

Dead space ate 24 units on a low-volume draw. Tiny impact at 1.7mg, massive impact at 0.25mg.

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u/rina_bergstrom24 points·1 months ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/emil_okwuosa19 points·1 months ago

Dead space ate 12 units on a low-volume draw. Tiny impact at 5mg, massive impact at 2.5mg.

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u/swirl_dont_shakeMOD19 points·1 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/saskia_mwangi13 points·1 months ago

Cosigning. The concentration on the vial in marker is load-bearing.

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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