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c/newbiequestions·posted 7 months ago by u/britta_boateng

the week one thing finally clicked for me and I want to write it down

Wiki Clean Column ×9 Slow Clap ×2

Been lurking in c/hplc for about 24 months and finally have something worth posting.

Short version: week 85, 15mg, and what is is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 31 threads, and the answers split roughly down the middle.

What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 79.

1,958 up / 320 down86% upvoted56 commentsid 1svmtc31 Dec 2025

56 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/halima_mbeki193 points·6 months ago
batch number?
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u/gentle_correctionnice about it68 points·6 months ago

Strongly agree. No question is dumb here.

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u/erez_perrin92 points·6 months ago

no question too basic, read the wiki first, then ask anyway

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u/mateusz_adebayo89 points·6 months ago

pens versus vials, same molecule, different price

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u/tidy_vialdrawer_pls129 points·6 months ago

Not convinced. The evidence does not support that reading.

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u/runa_grimaldi96 points·6 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/britta_boatengOP74 points·6 months ago

The what is question took me three weeks to understand. Wiki explained it eventually.

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[deleted]32 points·6 months ago

[deleted]

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u/britta_boateng100 points·7 months ago·edited

Titration means going slow. The 0.5mg is the starter, not the dose you stay on, not the dose you need to feel it.

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u/renzo_yildiz65 points·7 months ago·edited

week two nothing happening — yes, that is normal

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u/ines_ekstrom22 points·6 months ago

What does the wiki say?

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u/yusuf_kirchner74 points·6 months ago

the beginner question is not dumb

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u/dario_bakken57 points·6 months ago

what is bac water — bacteriostatic water, preservative included

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u/britt_abubakar18 points·6 months ago

I am going to push back on this slightly.

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u/karma_irrelevant17 points·6 months ago

link the wiki instead of retyping, but politely

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u/teodor_jansen52 points·7 months ago

pens versus vials, same molecule, different price

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u/sofia_petrescu19 points·7 months ago

pens versus vials, same molecule, different price

Yes, exactly this, and it is the bit that took me 55 weeks to accept.

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u/teodor_jansen10 points·7 months ago

This is a good question, genuinely.

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u/enzo_fonseca12 points·6 months ago

be kind, condescending answers are removed

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u/asks_dumb_questions7 points·6 months ago

This is a good question, genuinely.

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u/saskia_bakker4 points·6 months ago

Are you on a pen or vial?

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u/curious_panel_only36 points·6 months ago

rudeness is removed faster than bad questions

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u/ms_fragmenter10 points·6 months ago

Pens or research vials?

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u/renal_outcomes_rnephro-curious22 points·6 months ago

what is a COA — certificate of analysis, document from the lab

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u/ilias_cabrera18 points·6 months ago

is this normal week 11 — yes, probably

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u/teodor_jansen12 points·6 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/wholesome_lurker27 points·6 months ago

Are you on a pen or vial?

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u/greta_chukwu16 points·6 months ago

link the wiki instead of retyping, but politely

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u/aurel_boateng15 points·6 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/arne_restrepo12 points·6 months ago

Small correction: the trial was 7 weeks, not 16. Does not change your point but people will quote it.

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