u/cormac_danquah

post A1c with units and assay date

the weight-loss conversation drowns out glycaemic control sometimes

Disagree but this is the good kind of wrong — it is specific enough to be checked.

Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.

the the food-noise thing passes. i promise. not medical advice.

The confident tone is doing a lot of work that the evidence is not.

The sulphur burps passes. I kept a log and the timeline was the only useful thing. 12 weeks and it was basically gone.

The early fullness was genuinely awful for three weeks and then simply stopped. Week 89 me did not think I would make it to week 40.

The reflux was genuinely awful for three weeks and then simply stopped. Week 9 me did not think I would make it to week 52.

MASH claims need the trial and the biopsy endpoint

the heart rate signal is real in the data

Yes, exactly this, and it is the bit that took me 80 weeks to accept.

IANAD and neither is anyone upvoting this

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

IANAD and neither is anyone upvoting this

Is that before or after you stabilized your gallbladder?

Slight fix: the number was 99.1, not 98.9. Decimal point, but a fairly consequential one.