tried GIP for 23 weeks. here is what happened.
Posting this as a discussion rather than a claim: tried GIP for 23 weeks. here is what happened.
Numbers, in the order they matter: 23 weeks.
The step schedule question, answered properly, because it comes up weekly.
The label sets a minimum interval of four weeks between increases. That is a floor on how fast you may go, and it exists because tolerability, not efficacy, is what limits most people. There is nothing in the pharmacology that says you must increase at four weeks, or at eight, or ever.
What decides it in practice is whether the effect you want is still there. If appetite is quiet and the trend is going the right way, the dose is doing its job. If both have genuinely gone flat for six weeks or more, that is a conversation worth having with someone who knows your history.
Week 54 was the first time the scale moved after a five-week stall. I changed nothing in that window.
If two or three other people have done the same thing we might actually learn something. Alone it is an anecdote.
best — the order this archive was captured in
Vials and pens carry the same molecule; what differs is fill volume, device tolerance and whether you are doing your own arithmetic. Neither is inherently more accurate.
switching from sema is not a dose conversion, there is no clean equivalence
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme.
Saving this one. It is the clearest statement of the stall problem I have read here.
hold the dose that works, the ladder is not a leaderboard
Same experience with the appetite effect being flatter across the week rather than front-loaded.
if 7.5 is working, 10 is not automatically better
the appetite effect is blunter than sema, in a good way, most weeks
Careful with "everyone tolerates it better". The people it did not suit stop posting, which makes this board look calmer than the drug is.
Are you comparing yourself with the trial mean or with the people who post the most?
Switching from semaglutide, since three people asked in this thread alone.
There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.
None of that is a recommendation. It is what the threads say, and the threads are not a clinic.
zepbound and mounjaro are the same compound with different labels
the four-week step schedule is the label, not folklore
- 1switching from sema is not a dose conversion, there is no clean equivalence10 comments in this branch · started by u/ferran_mensah