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c/tapering·submitted 1 year ago by u/vial_math_vera

anyone else notice discontinuation kicking in around week 29

Trial Databranch of 6 comments

Right, the tapering question again, but with numbers this time. I have 20 data points over 4 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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6 comments, started 1 year ago
u/lane_watchermod · logistics204 points·1 year ago

Which country? Half the answers in this thread only apply in France.

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u/dario_stanescu135 points·1 year ago

the regain is treatment of chronic condition ending, not failure

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u/lift_heavy_thingsresistance training40 points·1 year ago·edited

Yeah, regain is not a failure.

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u/rina_bergstrom46 points·1 year ago·edited

regain on taper is expected, plan for it

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u/controversial_only27 points·1 year ago

regain on taper is expected, plan for it

Yes, exactly this, and it is the bit that took me 30 weeks to accept.

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u/coldchain_karencold chain8 points·1 year ago·edited

This is correct. Discontinuation data is real.

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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