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Single comment threadYou are looking at one branch of Germany: discontinuation, and what it actually costs here — 21 comments in the full submission. View in context.
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c/tapering·submitted 4 months ago by u/chidi_vermeulen

Germany: discontinuation, and what it actually costs here

Regainbranch of 8 comments

Posting this because I searched for it and got nothing useful. Setup: 0.5mg, week 89, injection-site soreness present but not ruining anything. I changed exactly one variable — discontinuation — and tracked it for 18 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else…

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8 comments, started 4 months ago
u/neha_krastev29 points·4 months ago

regain on taper is expected, plan for it

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u/zeynep_villalobos18 points·4 months ago

regain on taper is expected, plan for it

Yes, exactly this, and it is the bit that took me 4 weeks to accept.

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u/chidi_vermeulenOP12 points·4 months ago·edited

regain on taper is expected, plan for it Yes, exactly this, and it is the bit that took me 4 weeks to accept.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/appeal_letter_al-33 points·4 months ago

Strongly agree. The regain is expected.

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u/neha_mwangi34 points·4 months ago

appetite return timelines vary regain

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u/arne_restrepo26 points·4 months ago

regain on taper is expected, plan for it

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u/ferran_krastev14 points·4 months ago

What are you comparing it against though?

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u/maintenance_mode_maxmaintenance7 points·4 months ago

coming off deliberately, not by accident

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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