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Single comment threadYou are looking at one branch of genuine question about biopsy that I am slightly embarrassed to ask — 14 comments in the full submission. View in context.
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c/survodutide·submitted 1 months ago by u/joaquin_ivaturi

genuine question about biopsy that I am slightly embarrassed to ask

Questionbranch of 4 comments

dual agonist. That is the whole post, but I will justify it. Everything else people worry about in c/meta is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort dual agonist out first, and almost nobody does. I say this having got it wrong for 18 months. My…

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4 comments, started 1 months ago
u/renzo_asante24 points·1 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/injection_site_iris-23 points·1 months ago

Strongly agree. The safety story is separate.

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u/slow_logbook_notes301 point·1 months ago

MASH claims need the trial and the biopsy endpoint

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u/endotoxin_elliemicro6 points·1 months ago

the GLP-1/glucagon dual is hepatic fat, different from GIP/GLP-1

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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