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c/survodutide·submitted 2 years ago by u/cormac_danquah

19 months in and hepatic fat is still the thing I get wrong

Trial Databranch of 4 comments

Been lurking in c/t2dglp1 for about 23 months and finally have something worth posting. Short version: week 7, 1.7mg, and hepatic fat is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 29 threads, and the answers split roughly down the middle. What I actually want to know…

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4 comments, started 2 years ago
u/julia_mensa40 points·2 years ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/cold_chromatogram_only-28 points·2 years ago

the heart rate signal is real in the data

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u/cormac_danquah1 point·2 years ago

the heart rate signal is real in the data

Yes, exactly this, and it is the bit that took me 80 weeks to accept.

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u/nadia_bakker9 points·2 years ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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