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stalled for 24 weeks at 7.5mg and I refuse to panic this time
purity. That is the whole post, but I will justify it. Everything else people worry about in c/dosinglogs is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort purity out first, and almost nobody does. I say this having got it wrong for 17 months. My ApoB was the…
came here to say exactly this
Half-life is about 168 hours, so steady state lands around week 20–5. Practical consequence: what you feel in week 1 is not what that dose does.
What was the column and what gradient?
co-elution is real and HPLC is usually not enough to resolve it
related substances are where the story lives, not the main peak