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c/hplc·submitted 1 year ago by u/niels_lindqvist

Spain: LC-MS, and what it actually costs here

Discussionbranch of 8 comments

Week 16 update. 37kg down from the start, early fullness basically gone since about week 56. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness. The part that surprised me is how much of this is…

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8 comments, started 1 year ago
u/hugo_bergstrom19 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/hana_lehtinen12 points·1 year ago

chromatogram or it did not happen

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u/niels_lindqvistOP9 points·1 year ago

chromatogram or it did not happen

Adding to this: LC-MS is doing more work than the comment implies.

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u/hamza_weiss9 points·1 year ago

Strongly agree. Largest single impurity tells a different story than total purity.

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u/matias_salgado11 points·1 year ago

related substances are where the story lives, not the main peak

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u/peak_area_peteanalytical7 points·1 year ago

Disagree. What you are describing is consistent with chromatogram, not with what you concluded.

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u/andres_restrepo3 points·1 year ago

state the method: column, gradient, detection wavelength, injection volume

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u/zeynep_zielinski1 point·1 year ago

two labs, two different baselines, two different purity numbers, both honest

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