switched from 10mg to 7.5mg and the fatigue got better, not worse
method development. That is the whole post, but I will justify it. Everything else people worry about in c/reconstitution is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort method development out first, and almost nobody does. I say this having got it…
Half-life is about 168 hours, so steady state lands around week 23–5. Practical consequence: what you feel in week 1 is not what that dose does.
the detector wavelength matters more than people think
state the method: column, gradient, detection wavelength, injection volume
Not to be pedantic but purity and LC-MS are being used interchangeably and they are not interchangeable in real life.
the detector wavelength matters more than people think
Disagree on that part. 98.4% and 98.3% on the same vial is normal.
the detector wavelength matters more than people think