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c/glp1aus·posted 2 years ago by u/border_paperwork

the Australia question that gets asked weekly, answered properly

Discussion Well Actually ×9

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking PBS against ApoB for 3 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

993 up / 309 down76% upvoted19 commentsid 65d5fs7 Jun 2024

19 comments

15 in this archive, depth 5

best — the order this archive was captured in

u/tl_dr_tina83 points·2 years ago

Mechanistically the bit that matters is shortage. It explains most of the early profile and a decent chunk of the outcome.

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u/kenji_kimani43 points·2 years ago·edited

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/honest_syringe3310 points·2 years ago

TGA shortage notices are temporary

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u/sarcopenia_watch30 points·2 years ago

Week 7 for me and the honest summary is: 25kg down, muscle cramps manageable, and I have thought about food maybe four times today.

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u/viktor_laurent-24 points·2 years ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/border_paperworkOP1 point·2 years ago

Ireland here. Waited 3 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/hedda_adeyemi1 point·2 years ago·edited

TGA shortage notices are temporary

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u/peptidemeter_pat1 point·2 years ago

Disagree. What you are describing is consistent with shortage, not with what you concluded.

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u/border_paperworkOP1 point·2 years ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/aussie_pbs_watchAU29 points·2 years ago

the regulatory PBS is the blocker

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u/border_paperworkOP11 points·2 years ago

Stalled for 21 weeks, changed nothing, and it started moving again on week 27.

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u/hedda_adeyemi7 points·2 years ago

unfunded-means-full-price is the NZ reality

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u/blunt_coldbox_20249 points·2 years ago·edited

Strongly agree. AU and NZ differ.

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u/arne_ndiaye7 points·2 years ago

New Zealand is different on the two sides

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u/gustav_solberg5 points·2 years ago·edited

Strongly agree. AU and NZ differ.

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About c/glp1aus

Australia and New Zealand: PBS listing status and what it does to out-of-pocket cost, TGA shortage notices, the 2024 compounding rule change that closed a major access route overnight, and NZ's unfunded-means-full-price reality.

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