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c/glp1aus·posted 1 months ago by u/jarno_adeyemi

three years of TGA threads, summarised so you do not have to read them

TGA The Quiet One ×5

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking PBS against ApoB for 33 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

559 up / 49 down92% upvoted18 commentsid 1a44jb25 Jun 2026

18 comments

18 in this archive, depth 4

best — the order this archive was captured in

u/rafael_ostergaard82 points·1 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/noor_hovland58 points·1 months ago

unfunded-means-full-price is the NZ reality

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u/cormac_danquah24 points·1 months ago

Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.

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u/adnan_sandvik45 points·1 months ago

What is the PBS status?

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u/ignacio_vanhecke35 points·1 months ago

the 2024 compounding rule change closed a major route overnight

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u/noor_hovland37 points·1 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/nz_unfundedMOD26 points·1 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/jarno_adeyemiOP14 points·1 months ago

Yeah, the 2024 rule change was sudden.

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u/chidi_yilmaz3 points·1 months ago

TGA watches change monthly, follow the list

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u/cormac_danquah2 points·1 months ago

unfunded-means-full-price is the NZ reality

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u/border_paperwork25 points·1 months ago·edited

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/amara_kuipers15 points·1 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/sten_rautio5 points·1 months ago

the the UK versus the UK distinction is real

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u/adnan_sandvik3 points·1 months ago

the the UK versus the UK distinction is real

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/chidi_yilmaz2 points·1 months ago

TGA shortage notices are temporary

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u/careful_gradient_again20 points·1 months ago

Sceptical.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/hamza_serrano9 points·1 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/noor_hovland5 points·1 months ago

TGA watches change monthly, follow the list

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About c/glp1aus

Australia and New Zealand: PBS listing status and what it does to out-of-pocket cost, TGA shortage notices, the 2024 compounding rule change that closed a major access route overnight, and NZ's unfunded-means-full-price reality.

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