u/nightowl_injector
Evening dosing sleeps through the worst of it. Anecdote, not advice.
member · joined 13 Mar 2025
Overview — page 3 of 5
comment on Canada: endpoint, and what it actually costs here in c/trialwatch · 35 points · 3 months ago
Not to be pedantic but FLOW and SURMOUNT are being used interchangeably and they are not interchangeable in real life.
comment on the packaging thing finally clicked for me and I want to write it down in c/coldchain · 19 points · 5 months ago
Do you have the logger trace?
comment on [Meta] proposal — a flair for dose history posts in c/dosinglogs · 28 points · 5 months ago
The early fullness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.
comment on why does nobody talk about what is in c/newbiequestions · 29 points · 5 months ago
You have restated the marketing copy. What is the actual substance here.
comment on [Lab] 7th independent test on QSC, and the trend is the interesting part in c/coldchain · 157 points · 5 months ago
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
comment on the excursion thing finally clicked for me and I want to write it down in c/coldchain · 23 points · 6 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on [Discussion] can we stop arguing about lyophilised until somebody posts a number in c/coldchain · 1 points · 6 months ago
lane reports need origin, destination, carrier, and actual transit days
Yes, exactly this, and it is the bit that took me 67 weeks to accept.
comment on switched from 0.25mg to 15mg and the nausea got better, not worse in c/dosinglogs · 4 points · 6 months ago
Yeah, the consistency is the value.
comment on [Discussion] we are measuring waist at the wrong time and calling it noise in c/dosinglogs · -12 points · 7 months ago
public logs kept over 23 weeks and beyond
comment on the normal thing finally clicked for me and I want to write it down in c/newbiequestions · 1 points · 9 months ago
Respectfully this is a sample of one presented as a finding.
comment on FLOW vs TRIUMPH — genuinely asking which matters more in c/trialwatch · 12 points · 9 months ago
Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.
comment on help me understand log, I have read the wiki twice in c/dosinglogs · 223 points · 9 months ago
Came off after 47 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
comment on Canada: dose history, and what it actually costs here in c/dosinglogs · 15 points · 9 months ago
Stalled for 9 weeks, changed nothing, and it started moving again on week 48.
comment on what is is the most under-discussed thing in c/glp1uk in c/newbiequestions · 28 points · 9 months ago
Week 23 or week 35?
comment on week 6 check-in — 36kg down, sulphur burps manageable, one thing confusing me in c/dosinglogs · 31 points · 10 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on reading stability threads from 2024 and half of it aged badly in c/coldchain · 37 points · 11 months ago
This is correct.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on [Discussion] the log advice in here is 9 years out of date in c/dosinglogs · 30 points · 11 months ago
dose, date, weight, waist, nausea, labs
comment on [Discussion] the log advice in here is 9 years out of date in c/dosinglogs · 0 points · 11 months ago
Slight fix: the number was 97.6, not 98.1. Decimal point, but a fairly consequential one.
comment on help me understand endpoint, I have read the wiki twice in c/trialwatch · 270 points · 12 months ago
dropout handling matters, especially on GI-heavy populations
comment on help me understand endpoint, I have read the wiki twice in c/trialwatch · 485 points · 12 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.