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c/survodutide·submitted 3 months ago by u/meera_sandvik

tried MASH for 15 weeks. here is what happened.

Trial Databranch of 5 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking survodutide against ApoB for 31 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…

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5 comments, started 3 months ago
u/liver_enzyme_liz12 points·3 months ago
it is in the wiki actually
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u/cato_girard5 points·3 months ago

the MASH indication changes the risk calculus

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u/meera_sandvikOP4 points·3 months ago

rodent dual agonist is investigation only

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u/cato_batista3 points·3 months ago

the safety profile is not just tirzepatide amplified

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u/meera_sandvikOP1 point·3 months ago

Came off after 5 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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