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c/survodutide·submitted 1 year ago by u/diego_szabo

[Question] how do you actually verify biopsy

Questionbranch of 5 comments

Confession thread, sort of. I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 10 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have muscle…

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5 comments, started 1 year ago
u/protein_first_pnutrition7 points·1 year ago

the heart rate signal is real in the data

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[removed]3 points·1 year ago

[removed by moderator]

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u/kaia_wojcik1 point·1 year ago

[removed by moderator]

Yes, exactly this, and it is the bit that took me 86 weeks to accept.

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u/yannick_petrov10 points·1 year ago·edited

Strongly agree. The safety story is separate.

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u/kaia_wojcik6 points·1 year ago

Week 55 for me and the honest summary is: 23kg down, reflux manageable, and I have thought about food maybe four times today.

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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