someone explain chromatogram to me like I have not read a paper in years
chromatogram. That is the whole post, but I will justify it. Everything else people worry about in c/reconstitution is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort chromatogram out first, and almost nobody does. I say this having got it wrong for 23…
two labs, two different baselines, two different purity numbers, both honest
Respectfully this is a sample of one presented as a finding.
related substances are where the story lives, not the main peak
a round-robin on baseline integration would be genuinely useful
Sceptical. If this were true we would see it reflected in the data and we do not.
the detector wavelength matters more than people think
the gradient is doing the separation work, not the column alone
integration decision on a shoulder changes your number by half a point on its own