[Question] Ireland — has anyone got a straight answer on method development
gradient. That is the whole post, but I will justify it. Everything else people worry about in c/reconstitution is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort gradient out first, and almost nobody does. I say this having got it wrong for 6 months. My fasting…
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
Inter-lab variance on this kind of assay is routinely 1–2 points.
Disagree on that part. 98.1% and 98.3% on the same vial is normal.
Sceptical. If this were true we would see it reflected in the data and we do not.
Strongly agree. Largest single impurity tells a different story than total purity.
axis labels included, always
You have restated the marketing copy. What is the actual substance here.
the gradient is doing the separation work, not the column alone