u/yannick_salinas
Contributes reviews on supplier material. Based in Ilorin.
member · joined 16 Jul 2025
Comments — page 2 of 5
comment on [Question] New Zealand — has anyone got a straight answer on normal in c/newbiequestions · 1 points · 5 months ago
the first time question is not dumb
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · 38 points · 5 months ago
the co-agonism question is real and interesting
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 16 points · 5 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 18 points · 7 months ago
ATTAIN and ACHIEVE are phase 11 trials
comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 38 points · 7 months ago
Strongly agree. The supply impact would be huge.
comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 41 points · 7 months ago
Stalled for 24 weeks, changed nothing, and it started moving again on week 9.
comment on [Meta] the first time rule is doing its job and people should stop complaining in c/newbiequestions · 1 points · 7 months ago
Week 16 checking in: nothing on the scale, no nausea, wondering if the pen is broken. No, it is just week 16.
comment on tried STEP for 14 weeks. here is what happened. in c/trialwatch · 87 points · 7 months ago
Dead space in the needle hub holds a small but non-trivial volume.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on [Discussion] we are measuring first time at the wrong time and calling it noise in c/newbiequestions · 1 points · 8 months ago
what is titration — it means going slow on the escalation
comment on reading SURPASS threads from 2024 and half of it aged badly in c/trialwatch · 19 points · 8 months ago
Respectfully this is a sample of one presented as a finding.
comment on what would you tell week-1 you about ATTAIN in c/orforglipron · 73 points · 8 months ago
Slight fix: the number was 94.2, not 95.1. Decimal point, but a fairly consequential one.
comment on what would you tell week-1 you about ATTAIN in c/orforglipron · 68 points · 8 months ago
small molecule purity is different testing than peptides
comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 12 points · 9 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 4 points · 9 months ago
the supply conversation changes if this approves
comment on [Results] 42 weeks, 25kg, and co-agonism was the hard part in c/cagrilintide · 24 points · 9 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on what is is the most under-discussed thing in c/glp1uk in c/newbiequestions · 99 points · 9 months ago
what is a COA — certificate of analysis, document from the lab
comment on reading phase 2 threads from 2024 and half of it aged badly in c/retatrutide · 7 points · 10 months ago
That is net peptide content, not purity.
Yes, exactly this, and it is the bit that took me 88 weeks to accept.
comment on week 91 check-in — 37kg down, early fullness manageable, one thing confusing me in c/trialwatch · 3 points · 10 months ago
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
comment on week 91 check-in — 37kg down, early fullness manageable, one thing confusing me in c/trialwatch · 1 points · 10 months ago
give the trial name, phase, n, and primary endpoint in the body
comment on [Results] 61 weeks on 2.4mg, full numbers, ask me anything boring in c/retatrutide · 134 points · 1 year ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.