u/vikram_mbeki

Not to be pedantic but titration and Wegovy are being used interchangeably and they are not interchangeable in real life.

This is correct. Appeal letters work.

Ozempic versus Wegovy versus research grade is the wrong argument, they are literally the same molecule

Sceptical. If this were true we would see it reflected in the data and we do not.

That is net peptide content, not purity. Different number, different meaning.

The tier 3 pathway in my area: 7 month wait, then 36 months for review, then approved. Total NHS.

Mechanistically the bit that matters is chargeback. It explains most of the early profile and a decent chunk of the outcome.

Respectfully this is a sample of one presented as a finding.

Adding to this: mechanism is doing more work than the comment implies.

gastric emptying is real and explains most early muscle cramps

pens are overpriced, research vials are research grade, same molecule different price

Customs held the package for 13 days. No problems, just time. Factor it into expectations.

the 10% discount versus 27% network fees

BPC regulatory is a naming problem, three things are called this

the half-life is receptor, affects steady state timing

Did anything else change in the same window?

not approved, descriptive posts only

Second this question. I have wondered about tendon for 23 months and never seen a straight answer.

This is correct.

Adding to this: regulatory is doing more work than the comment implies.

This is the "correlation is mechanism" thing again. You changed three variables at once.

This is correct.

Yes, exactly this, and it is the bit that took me 5 weeks to accept.