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what would you tell week-1 you about secretagogue
Something I noticed reading old threads that I have not seen said out loud. The advice on secretagogue in this community changed substantially around the start of last…
u/throwaway_wl2026
Made this to ask about something embarrassing. It was not embarrassing at all.
throwaway account · joined 13 Apr 2025
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Overview — page 2 of 4
comment on [Meta] proposal — a flair for resistance training posts in c/glp1muscle · 7 points · 5 months ago
no supplement selling, no coaching solicitation
comment on what would you tell week-1 you about secretagogue in c/researchpeptides · 1 points · 5 months ago
evidence-level statements required: in vitro, rodent, or human
comment on what would you tell week-1 you about secretagogue in c/researchpeptides · 12 points · 5 months ago
Week 72 for me and the honest summary is: 48kg down, reflux manageable, and I have thought about food maybe four times today.
comment on [Question] the UK — has anyone got a straight answer on ATTAIN in c/orforglipron · 32 points · 5 months ago
small molecule, not a peptide, purity discussion is different
comment on the ACHIEVE question that gets asked weekly, answered properly in c/orforglipron · 4 points · 6 months ago
phase 13 data is interesting, phase 34 will tell the real story
comment on am I the only one who found protein harder than the injections in c/glp1muscle · -21 points · 6 months ago
This is correct. DEXA is the standard.
comment on what would you tell week-1 you about handling in c/researchpeptides · 5 points · 7 months ago
everything else in the vial drawer, secretagogue
comment on dual agonist — my 21-week log, condensed into one table in c/survodutide · 1 points · 7 months ago
Half-life is about 168 hours, so steady state lands around week 2–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on three years of protein threads, summarised so you do not have to read them in c/glp1muscle · 55 points · 8 months ago
bathroom BIA scales are not a method
comment on am I the only one who found TB-500 harder than the injections in c/researchpeptides · 20 points · 8 months ago
supply-chain naming is a mess, ask for HPLC
comment on [Question] how do you actually verify oral GLP-1 in c/orforglipron · 8 points · 10 months ago
Half-life is about 168 hours, so steady state lands around week 13–5.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on [Discussion] we are measuring MASH at the wrong time and calling it noise in c/survodutide · 4 points · 10 months ago
This is correct. Do not generalise from tirzepatide.
comment on why does nobody talk about SURPASS in c/tirzepatide · 98 points · 11 months ago
the appetite change on tirz is more than just reduced hunger, it is different machinery
comment on anyone else notice tirzepatide kicking in around week 20 in c/tirzepatide · 23 points · 1 year ago
the dual agonism hits different and that is why people describe it differently
comment on reading Zepbound threads from 2024 and half of it aged badly in c/tirzepatide · 136 points · 1 year ago
Zepbound and Mounjaro are literally the same drug, the name is the only difference
comment on 6 months in and glucagon is still the thing I get wrong in c/survodutide · 15 points · 1 year ago
Strongly agree. The safety story is separate.
comment on anyone else notice resistance training kicking in around week 75 in c/glp1muscle · 7 points · 1 year ago
Did anything else change in the same window?
comment on unpopular opinion: FFMI is massively overrated in c/glp1muscle · 1 points · 1 year ago
no supplement selling, no coaching solicitation
comment on DEXA: what the trials say vs what this community says in c/glp1muscle · 1 points · 1 year ago
Strongly agree. Resistance training counts.