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u/thermal_mass_tom

A cold box is thermal mass plus insulation. Most kits get the insulation part wrong.

member · joined 16 Mar 2024

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comment on [Resolved] the QST batch dispute — vendor retested at their own cost, numbers matched, my error in c/scamalerts · 71 points · 2 days ago

this is the most niche offer on the internet and i want to take you up on it

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comment on [Failure] gel pack arrived liquid and warm in July. photos at unboxing. in c/coldchain · 176 points · 3 days ago

The specific failure here is almost certainly thermal mass rather than insulation. A single small pack in a large void has nothing to hold the temperature with; the pack exhausts and then the air in the box does whatever the outside is doing.

Two smaller packs plus a snugger void outperforms one bigger pack in a loose box, and it costs the same.

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comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · 43 points · 3 days ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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comment on [Data] logger trace: 6 days transit, 41 hours above 8°C, powder was fine in c/coldchain · 143 points · 3 days ago

the other thing a logger shows you is your own fridge. i put one in mine for a week expecting to be smug and found 2.1°C at the back and 7.8°C in the door.

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comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 63 points · 4 days ago

Titration speed is a side-effect dial far more than an efficacy dial.

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comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 4 points · 5 days ago

Stalled for 8 weeks, changed nothing, and it started moving again on week 38.

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comment on A1c 9.1 → 5.4 over 14 months, full table inside in c/bloodwork · 0 points · 9 days ago

nobody here can tell you what a result means for you

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comment on how many independent tests before you trust a vendor. my number is three in c/vendorvetting · 73 points · 10 days ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on [Vendor] BCH sent the wrong compound and fixed it in 48 hours in c/vendorvetting · 3 points · 12 days ago

Not to be pedantic but order records and PeptideMeter are being used interchangeably and they are not interchangeable in real life.

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comment on [Resolved] the QST batch dispute — vendor retested, numbers matched, my error in c/vendorvetting · 2 points · 28 days ago

one vendor per post, multi-vendor goes in the monthly thread

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comment on [Discussion] glucagon is doing more work than we give it credit for in c/survodutide · 2 points · 1 months ago

the MASH indication changes the risk calculus

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comment on stalled for 14 weeks at 5mg and I refuse to panic this time in c/sideeffects · 10 points · 1 months ago

resting heart rate moved up 20 bpm and settled back down when I stopped escalating

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comment on week 76 check-in — 26kg down, fatigue manageable, one thing confusing me in c/bloodwork · 6 points · 1 months ago

eGFR noise during rapid loss is expected

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comment on group buy organiser vanished with 3.4k. here is the timeline in c/vendorvetting · 126 points · 1 months ago

This order history matches mine almost exactly. Same vendor, same timeframe, same result.

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comment on reading bloodwork threads from 2024 and half of it aged badly in c/bloodwork · 54 points · 2 months ago

What are your reference ranges?

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comment on baseline labs — 12 things I got wrong before I got it right in c/bloodwork · 2 points · 2 months ago

Slight fix: the number was 97.6, not 98.3.

Disagree on that part. 98.1% and 98.9% on the same vial is normal.

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comment on baseline labs — 12 things I got wrong before I got it right in c/bloodwork · 53 points · 2 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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comment on [Discussion] the reflux advice in here is 18 years out of date in c/sideeffects · 37 points · 2 months ago

genuinely useful, thanks

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comment on what would you tell week-1 you about biopsy in c/survodutide · 23 points · 3 months ago

glucagon co-agonism has a different safety story

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