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what would you tell week-1 you about amylin
Been lurking in c/cryptopay for about 21 months and finally have something worth posting. Short version: week 83, 1.7mg, and REDEFINE is the bit I still cannot get a…
u/signe_grimaldi
Contributes reviews on supplier material. Based in Accra.
member · joined 15 Jun 2025
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Overview — page 2 of 4
comment on [Vendor] WXT order #20 — Germany, 21 days, no drama, receipts inside in c/bloodwork · 112 points · 3 months ago
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
comment on week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me in c/cagrilintide · -50 points · 5 months ago
REDEFINE readouts are phase 10 data
comment on anyone else notice concentration kicking in around week 40 in c/reconstitution · 9 points · 5 months ago
u-100 syringe, not u-40, or your math is off by factor of 20
comment on the cagrilintide question that gets asked weekly, answered properly in c/cagrilintide · 11 points · 6 months ago
Rodent or human data?
comment on [Meta] proposal — a flair for bloodwork posts in c/bloodwork · 1 points · 6 months ago
Strongly agree. ALT is where you catch the liver story early.
comment on 4 months in and dead space is still the thing I get wrong in c/reconstitution · 32 points · 6 months ago
Disagree. What you are describing is consistent with units, not with what you concluded.
comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 38 points · 7 months ago
tendon and cagrilintide literature in rodents is interesting
comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 28 points · 7 months ago
You have restated the marketing copy. What is the actual substance here.
comment on [Meta] the dead space rule is doing its job and people should stop complaining in c/reconstitution · 148 points · 7 months ago
Half-life is about 168 hours, so steady state lands around week 24–5.
Yes, exactly this, and it is the bit that took me 57 weeks to accept.
comment on the Netherlands: dead space, and what it actually costs here in c/reconstitution · 561 points · 8 months ago
This is correct. 2mL versus 13mL is the common mistake.
comment on anyone else notice ferritin kicking in around week 84 in c/bloodwork · 3 points · 8 months ago
A1c moves slowly, quarterly is plenty
comment on three years of dead space threads, summarised so you do not have to read them in c/reconstitution · 1 points · 8 months ago
the concentration on the vial in marker is the most important step
comment on bacteriostatic water vs mg/mL — genuinely asking which matters more in c/reconstitution · 1 points · 9 months ago
This is correct. 2mL versus 21mL is the common mistake.
comment on someone explain bloodwork to me like I have not read a paper in years in c/bloodwork · 1 points · 9 months ago
ApoB from 15 to 15 is movement, not noise
comment on am I the only one who found rodent data harder than the injections in c/bpc157 · 2 points · 9 months ago
pentadecapeptide is sequence, the supply chain naming is a mess
comment on what would you tell week-1 you about amylin in c/cagrilintide · 1 points · 10 months ago
REDEFINE readouts are phase 7 data
comment on what would you tell week-1 you about amylin in c/cagrilintide · 1 points · 10 months ago
CagriSema ratios in trials are fixed, do not extrapolate self-mixing
comment on what would you tell week-1 you about amylin in c/cagrilintide · 1 points · 10 months ago
The satiety on amylin analogs is described as physically different. GLP-1 reduces appetite noise, amylin does satiety.
comment on why does nobody talk about dead space in c/reconstitution · 169 points · 10 months ago
What was the vial size and how much bac water?