u/rt_shift_reggie

Yeah, that is totally normal for week 5.

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

press release hazard ratio posts must be flaired until a publication exists

Crossposting this to c/meta because the people who need it are not reading this community.

Not convinced. The evidence does not support that reading.

Half-life is about 168 hours, so steady state lands around week 17–5.

Yes, exactly this, and it is the bit that took me 45 weeks to accept.

SELECT reported a SURMOUNT hazard ratio but the absolute event rate is what changes clinical practice.

The confident tone is doing a lot of work that the evidence is not.

Sceptical. If this were true we would see it reflected in the data and we do not.

link the wiki instead of retyping, but politely

link the wiki instead of retyping, but politely

Yes, exactly this, and it is the bit that took me 74 weeks to accept.

Strongly agree. Pricing is local.

Respectfully this is a sample of one presented as a finding.

You have restated the marketing copy. What is the actual substance here.

link the wiki instead of retyping, but politely

Yes, exactly this, and it is the bit that took me 56 weeks to accept.

Yeah, that is totally normal for week 11.

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

Week 3 checking in: nothing on the scale, no nausea, wondering if the pen is broken. No, it is just week 3.

the discontinuation arms are the interesting part, not the STEP endpoints