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u/reflux_report

GERD got worse before it got better. Smaller meals, earlier dinner.

member · joined 21 Jul 2024

44,461post karma
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171comments

Overview — page 3 of 5

comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 180 points · 3 months ago

research use only, handling and analysis, not protocols

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comment on small win: exit scam stopped being a problem at week 56 in c/scamalerts · 1 points · 3 months ago

the reship offer that never sends anything is worth noting

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comment on [Lab] 17th independent test on QSC, and the trend is the interesting part in c/retatrutide · 1 points · 3 months ago

Slight fix: the number was 98.6, not 98.7. Decimal point, but a fairly consequential one.

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comment on [Lab] 17th independent test on QSC, and the trend is the interesting part in c/retatrutide · 61 points · 3 months ago

phase 2 numbers are not maintenance numbers, cite the trial

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comment on [Meta] proposal — a flair for certificate of analysis posts in c/coa · 26 points · 3 months ago

the counterion is part of the mass you paid for

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comment on [Discussion] bacteriostatic water is doing more work than we give it credit for in c/reconstitution · 8 points · 3 months ago

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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comment on the HPLC thing finally clicked for me and I want to write it down in c/hplc · 24 points · 4 months ago

This is the correct method framing. Column and gradient are load-bearing fields.

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comment on someone explain exit scam to me like I have not read a paper in years in c/scamalerts · 2 points · 4 months ago

no doxxing, company registration is fine, individuals are not

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comment on [Discussion] can we stop arguing about dead space until somebody posts a number in c/reconstitution · 108 points · 4 months ago

the concentration on the vial in marker is the most important step

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comment on my A1c moved and I cannot work out whether dead space is why in c/reconstitution · -19 points · 5 months ago

swirl, do not shake, or you are courting oxidation

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comment on week 16 check-in — 42kg down, constipation manageable, one thing confusing me in c/retatrutide · 28 points · 5 months ago

That is net peptide content, not purity. Different number, different meaning.

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comment on [Meta] proposal — a flair for resistance training posts in c/glp1muscle · 28 points · 5 months ago

Week 8 for me and the honest summary is: 47kg down, the food-noise thing manageable, and I have thought about food maybe four times today.

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comment on reading purity threads from 2024 and half of it aged badly in c/hplc · 45 points · 5 months ago

Gradient goblin mode: changed the solvent composition 11 times, finally got good resolution on a method development peak.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Lab] 14th independent test on QSC, and the trend is the interesting part in c/retatrutide · 192 points · 5 months ago

Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.

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comment on help me understand 2.4mg, I have read the wiki twice in c/semaglutide · 69 points · 5 months ago

Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.

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comment on protein is the most under-discussed thing in c/cagrilintide in c/glp1muscle · 10 points · 6 months ago

rapid loss plus no protein equals muscle loss

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comment on tried HPLC for 6 weeks. here is what happened. in c/hplc · 32 points · 6 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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comment on small win: TRIUMPH stopped being a problem at week 5 in c/retatrutide · 277 points · 6 months ago

What was the dosing schedule in that arm?

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comment on is it normal to get the food-noise thing at week 20 in c/glp1muscle · 9 points · 6 months ago

What are you comparing it against though?

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comment on 4 months in and dead space is still the thing I get wrong in c/reconstitution · 1 points · 6 months ago

never post a calculation as advice without stating the concentration

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