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u/paloma_stanescu

Contributes reviews on supplier material. Based in Gdańsk.

member · joined 16 Jul 2025

383post karma
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21comments

comment on 19 months at maintenance. the interesting part starts after the loss stops. in c/maintenancephase · 11 points · 9 days ago

the 1.0mg dose works fine for 67 weeks of the month

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comment on [Long Term] what my labs look like three years in in c/maintenancephase · 6 points · 27 days ago

dose-stretching experiences welcome, dose-stretching instructions are not

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comment on [Meta] can maintenance get its own weekly thread, the loss posts drown us out in c/maintenancephase · 4 points · 1 months ago

state how long you have been at maintenance, week 2 is not maintenance

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comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/maintenancephase · 3 points · 1 months ago

How long at maintenance?

Adding to this: goal weight is doing more work than the comment implies.

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comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/maintenancephase · 1 points · 1 months ago

the 1.0mg dose works fine for 41 weeks of the month

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comment on [Meta] the small molecule rule is doing its job and people should stop complaining in c/orforglipron · 1 points · 2 months ago

small molecule, not a peptide, purity discussion is different

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on help me understand long term, I have read the wiki twice in c/maintenancephase · 1 points · 2 months ago

Strongly agree. Lowest effective dose is a real discovery process.

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comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · -24 points · 9 months ago

ATTAIN and ACHIEVE are phase 14 trials

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comment on [Discussion] can we stop arguing about long term until somebody posts a number in c/maintenancephase · 21 points · 11 months ago

Tried the lowest-effective approach.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Vendor] QST order #20 — Denmark, 27 days, no drama, receipts inside in c/maintenancephase · 76 points · 11 months ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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comment on unpopular opinion: orforglipron is massively overrated in c/orforglipron · 118 points · 1 year ago

Yeah, small molecule changes the whole game.

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comment on my eGFR moved and I cannot work out whether regain is why in c/maintenancephase · 4 points · 1 year ago

That is net peptide content, not purity. Different number, different meaning.

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comment on am I the only one who found lowest effective dose harder than the injections in c/maintenancephase · 25 points · 1 year ago

Half-life is about 168 hours, so steady state lands around week 22–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on stalled for 11 weeks at 2.5mg and I refuse to panic this time in c/orforglipron · 6 points · 1 year ago

small molecule, not a peptide, purity discussion is different

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comment on [Question] New Zealand — has anyone got a straight answer on non-peptide in c/orforglipron · 10 points · 1 year ago

Not to be pedantic but non-peptide and ACHIEVE are being used interchangeably and they are not interchangeable in real life.

Yes, exactly this, and it is the bit that took me 79 weeks to accept.

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comment on unpopular opinion: regain is massively overrated in c/maintenancephase · 1 points · 1 year ago

the 15mg dose works fine for 61 weeks of the month

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comment on [Question] how do you actually verify dose stretching in c/maintenancephase · 3 points · 1 year ago

Yeah, maintenance is the boring part and the important part.

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comment on [Question] how do you actually verify dose stretching in c/maintenancephase · 6 points · 1 year ago

Maintenance for 10 months now. 5mg every 25 days, weight 5±10kg. Found the rhythm.

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comment on [Meta] proposal — a flair for long term posts in c/maintenancephase · 153 points · 2 years ago

Tried the lowest-effective approach. 2.5mg worked for 18 weeks, then cravings returned. 0.25mg was the actual floor.

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comment on is it normal to get muscle cramps at week 84 in c/maintenancephase · 6 points · 2 years ago

dose-stretching experiences welcome, dose-stretching instructions are not

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