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anyone else notice co-agonism kicking in around week 5
Been lurking in c/orforglipron for about 9 months and finally have something worth posting. Short version: week 6, 1.0mg, and amylin is the bit I still cannot get a…
u/nz_unfunded
NZ. Unfunded means full price. Full price here is genuinely absurd.
member · joined 22 Oct 2024
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Overview — page 3 of 5
comment on [PSA] Medutest is not what most of this community thinks it is in c/vendorvetting · 19 points · 6 months ago
Slight fix: the number was 97.6, not 98.1. Decimal point, but a fairly consequential one.
comment on [Meta] proposal — a flair for SURMOUNT posts in c/tirzepatide · 29 points · 6 months ago
stalled on sema, tried tirz, and the curves were actually different shapes
comment on is it normal to get the food-noise thing at week 75 in c/glp1aus · 8 points · 6 months ago
Strongly agree. AU and NZ differ.
comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 15 points · 6 months ago
This is correct. The co-agonism is real.
comment on [PSA] shortage is not what most of this community thinks it is in c/glp1aus · 62 points · 7 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on anyone else notice co-agonism kicking in around week 5 in c/cagrilintide · 135 points · 7 months ago
CagriSema is a fixed combo in trials, not user-mixed
Yes, exactly this, and it is the bit that took me 76 weeks to accept.
comment on anyone else notice 15mg kicking in around week 24 in c/tirzepatide · 1 points · 8 months ago
Not convinced. The evidence does not support that reading.
comment on [Discussion] we are measuring Australia at the wrong time and calling it noise in c/glp1aus · -34 points · 8 months ago
PBS/TGA claims need the notice or schedule entry
comment on [Question] New Zealand — what am I missing here in c/glp1aus · 23 points · 9 months ago
Tracking number removed. It identifies both ends of a shipment.
comment on is it normal to get nausea at week 10 in c/tirzepatide · 67 points · 9 months ago
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
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is it normal to get nausea at week 10
Week 95 update. 31kg down from the start, muscle cramps basically gone since about week 40. Things that worked: consistency, protein at breakfast, walking more than I…
comment on [Results] 42 weeks, 25kg, and co-agonism was the hard part in c/cagrilintide · 41 points · 9 months ago
Half-life is about 168 hours, so steady state lands around week 5–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on what would you tell week-1 you about amylin in c/cagrilintide · 1 points · 10 months ago
I am going to push back on this slightly.
comment on the vendor question that gets asked weekly, answered properly in c/vendorvetting · 46 points · 10 months ago
This order history matches mine almost exactly. Same vendor, same timeframe, same result.
comment on [Question] TGA — what am I missing here in c/glp1aus · 6 points · 10 months ago
the New Zealand versus New Zealand distinction is real
comment on genuine question about dual agonist that I am slightly embarrassed to ask in c/tirzepatide · 14 points · 10 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Discussion] the cagrilintide advice in here is 21 years out of date in c/cagrilintide · 110 points · 10 months ago
Disagree. What you are describing is consistent with CagriSema, not with what you concluded.
comment on [Discussion] we are measuring PBS at the wrong time and calling it noise in c/glp1aus · 7 points · 10 months ago
This is correct.
Adding to this: TGA is doing more work than the comment implies.
comment on [Discussion] we are measuring PBS at the wrong time and calling it noise in c/glp1aus · 60 points · 10 months ago
This is correct. PBS listings matter.