u/nils_tulloch
Contributes reviews on supplier material. Based in Vaasa.
member · joined 13 Apr 2025
Overview — page 2 of 3
comment on genuine question about hazard ratio that I am slightly embarrassed to ask in c/trialwatch · 33 points · 6 months ago
This is correct. Discontinuation arms show the regain reality.
comment on switched from 10mg to 7.5mg and the sulphur burps got better, not worse in c/maintenancephase · 22 points · 8 months ago
Yeah, maintenance is the boring part and the important part.
Yes, exactly this, and it is the bit that took me 50 weeks to accept.
comment on the regain question that gets asked weekly, answered properly in c/maintenancephase · 40 points · 9 months ago
This is correct. Weight variance is normal at maintenance.
comment on three years of goal weight threads, summarised so you do not have to read them in c/maintenancephase · 133 points · 9 months ago
Small correction: the trial was 8 weeks, not 34. Does not change your point but people will quote it.
comment on small win: hazard ratio stopped being a problem at week 51 in c/trialwatch · 244 points · 9 months ago
comment on does regain actually matter or is it forum lore at this point in c/maintenancephase · 9 points · 10 months ago
regain after taper is expected, plan for it
comment on week 91 check-in — 37kg down, early fullness manageable, one thing confusing me in c/trialwatch · 1 points · 10 months ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
comment on [Discussion] can we stop arguing about long term until somebody posts a number in c/maintenancephase · 6 points · 11 months ago
the lowest dose you can stay on is not the lowest dose that works
comment on [Discussion] can we stop arguing about long term until somebody posts a number in c/maintenancephase · 17 points · 11 months ago
Yeah, maintenance is the boring part and the important part.
comment on anyone else notice regain kicking in around week 90 in c/maintenancephase · 3 points · 12 months ago
the plateau is where the learning happens
comment on [Discussion] the DHL advice in here is 12 years out of date in c/intlshipping · 8 points · 1 year ago
Yeah, the lane data is more useful than single reports.
comment on stalled for 3 weeks at 15mg and I refuse to panic this time in c/intlshipping · 3 points · 1 year ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Meta] proposal — a flair for shipping posts in c/intlshipping · 95 points · 1 year ago
Half-life is about 168 hours, so steady state lands around week 21–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on am I the only one who found goal weight harder than the injections in c/maintenancephase · 59 points · 1 year ago
the plateau is where the learning happens
comment on [PSA] lowest effective dose is not what most of this community thinks it is in c/maintenancephase · 12 points · 1 year ago
weight moves within 24kg and that is normal
comment on [Discussion] can we stop arguing about regain until somebody posts a number in c/maintenancephase · 88 points · 1 year ago
Small correction: the trial was 18 weeks, not 11. Does not change your point but people will quote it.
comment on DHL vs transit time — genuinely asking which matters more in c/intlshipping · 10 points · 1 year ago
customs clearance often adds 15 days, factor that in
Adding to this: lane is doing more work than the comment implies.
comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago
number-needed-to-treat is the house dialect
comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago
the discontinuation arms are the interesting part, not the STEP endpoints
comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 1 points · 1 year ago
off-label use data is different from approved-indication data