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u/nightowl_injector

Evening dosing sleeps through the worst of it. Anecdote, not advice.

member · joined 13 Mar 2025

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Comments — page 2 of 4

comment on [Concluded] 104 weeks. final numbers. thanks for reading. in c/dosinglogs · 10 points · 19 days ago

include dose and date on every update

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comment on freezing reconstituted product: why the answer is no in c/coldchain · 15 points · 19 days ago

Which carrier and route?

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comment on freezing reconstituted product: why the answer is no in c/coldchain · 59 points · 20 days ago

Disagree. What you are describing is consistent with lyophilised, not with what you concluded.

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comment on [Data] 41 lanes, 900 data points, transit temperature by carrier in c/coldchain · 28 points · 24 days ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

Adding to this: excursion is doing more work than the comment implies.

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comment on [Results] 12 weeks, 35kg, and FLOW was the hard part in c/trialwatch · 0 points · 1 months ago

off-label use data is different from approved-indication data

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comment on why does nobody talk about hazard ratio in c/trialwatch · 8 points · 1 months ago

event rates are more informative than hazard ratios alone

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comment on Denmark: first time, and what it actually costs here in c/newbiequestions · 241 points · 1 months ago

Crossposting this to c/scamalerts because the people who need it are not reading this community.

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comment on [Meta] the log rule is doing its job and people should stop complaining in c/dosinglogs · 38 points · 1 months ago

consistency is harder than the dose change

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comment on small win: normal stopped being a problem at week 6 in c/newbiequestions · 78 points · 1 months ago

Not convinced.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Meta] proposal — a flair for first time posts in c/newbiequestions · 56 points · 2 months ago

the beginner question is not dumb

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comment on SELECT: the version I wish someone had shown me in week 1 in c/trialwatch · 159 points · 2 months ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on am I the only one who found stability harder than the injections in c/coldchain · 1 points · 2 months ago

gel packs last 16 hours, after that you are relying on the box itself

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comment on [Discussion] we are measuring SURPASS at the wrong time and calling it noise in c/trialwatch · 41 points · 2 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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comment on [Question] Ireland — has anyone got a straight answer on packaging in c/coldchain · 1 points · 2 months ago

Strongly agree. Peak temperature is not the whole story.

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comment on someone explain FLOW to me like I have not read a paper in years in c/trialwatch · 1 points · 3 months ago

the discontinuation arms are the interesting part, not the FLOW endpoints

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comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 151 points · 3 months ago

Yeah, absolute numbers matter more than the press release.

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comment on normal: what the trials say vs what this community says in c/newbiequestions · 11 points · 3 months ago

no question too basic, read the wiki first, then ask anyway

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comment on Canada: endpoint, and what it actually costs here in c/trialwatch · 35 points · 3 months ago

Not to be pedantic but FLOW and SURMOUNT are being used interchangeably and they are not interchangeable in real life.

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comment on the packaging thing finally clicked for me and I want to write it down in c/coldchain · 19 points · 5 months ago

Do you have the logger trace?

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comment on [Meta] proposal — a flair for dose history posts in c/dosinglogs · 28 points · 5 months ago

The early fullness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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