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Canada vs formulary — genuinely asking which matters more
Long-ish post, sorry. tl;dr at the bottom. I have been tracking Canada against eGFR for 11 weeks because I could not find anyone who had. The correlation is weaker than…
u/matias_salgado
Contributes reviews on supplier material. Based in Mombasa.
member · joined 15 Jun 2025
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Overview — page 2 of 4
comment on what changed for me between week 5 and week 48 in c/tirzepatide · 1 points · 5 months ago
That is net peptide content, not purity. Different number, different meaning.
comment on [Meta] proposal — a flair for Zepbound posts in c/tirzepatide · 19 points · 7 months ago
dual agonism is dual agonist, do not generalise from semaglutide
comment on switched from 7.5mg to 15mg and the nausea got better, not worse in c/tirzepatide · 20 points · 7 months ago
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
comment on the shipping question that gets asked weekly, answered properly in c/intlshipping · 21 points · 8 months ago
GGPeps ships from Denmark, arrival is 16 to 18 days on average
comment on formulary — 4 things I got wrong before I got it right in c/glp1canada · 10 points · 9 months ago
provincial formularies differ sharply
comment on 15 months in and purity is still the thing I get wrong in c/hplc · 442 points · 9 months ago
state the method: column, gradient, detection wavelength, injection volume
comment on is it normal to get injection-site soreness at week 54 in c/glp1canada · 220 points · 9 months ago
The confident tone is doing a lot of work that the evidence is not.
comment on my eGFR moved and I cannot work out whether HPLC is why in c/hplc · 307 points · 9 months ago
axis labels included, always
Yes, exactly this, and it is the bit that took me 41 weeks to accept.
comment on small win: chromatogram stopped being a problem at week 95 in c/hplc · 29 points · 10 months ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on genuine question about gradient that I am slightly embarrassed to ask in c/hplc · 1 points · 10 months ago
state the method: column, gradient, detection wavelength, injection volume
comment on switched from 12.5mg to 10mg and the nausea got better, not worse in c/tirzepatide · 1 points · 10 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on switched from 12.5mg to 10mg and the nausea got better, not worse in c/tirzepatide · 298 points · 10 months ago
I am going to push back on this slightly.
comment on Canada vs formulary — genuinely asking which matters more in c/glp1canada · 24 points · 11 months ago
Week 63 for me and the honest summary is: 11kg down, muscle cramps manageable, and I have thought about food maybe four times today.
comment on Canada vs formulary — genuinely asking which matters more in c/glp1canada · 61 points · 11 months ago
the 2 province variation is real
comment on Canada vs formulary — genuinely asking which matters more in c/glp1canada · 18 points · 11 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on [Question] how do you actually verify special authorization in c/glp1canada · 6 points · 11 months ago
This is correct. Name your province.
comment on three years of purity threads, summarised so you do not have to read them in c/hplc · 102 points · 1 year ago
What was the column and what gradient?
comment on [Meta] proposal — a flair for shipping posts in c/intlshipping · 242 points · 1 year ago
transit time variance is the story, not the average
comment on week 86 check-in — 6kg down, constipation manageable, one thing confusing me in c/glp1canada · 14 points · 1 year ago
Mechanistically the bit that matters is special authorization. It explains most of the early profile and a decent chunk of the outcome.