3.2k
6 months in and baseline labs is still the thing I get wrong
Genuinely asking, not being difficult. Everyone in c/meta repeats that ALT is important. I believe it, but I have never seen anyone show why, and when I search I get 9…
u/liver_enzyme_liz
ALT dropped 34 to 19. The fatty-liver story is the underrated one.
member · joined 14 Apr 2024
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Overview — page 2 of 5
comment on TRIUMPH: what the trials say vs what this community says in c/retatrutide · 18 points · 1 months ago
Slight fix: the number was 96.8, not 97.2. Decimal point, but a fairly consequential one.
comment on help me understand A1c, I have read the wiki twice in c/bloodwork · 0 points · 1 months ago
Do you have baseline to compare to?
comment on glucagon is the most under-discussed thing in c/scamalerts in c/survodutide · 13 points · 1 months ago
Mechanistically the bit that matters is glucagon. It explains most of the early profile and a decent chunk of the outcome.
comment on glucagon — 17 things I got wrong before I got it right in c/survodutide · 58 points · 2 months ago
Retitled to remove editorialising. Put the evidence in the body.
comment on reading bloodwork threads from 2024 and half of it aged badly in c/bloodwork · 111 points · 2 months ago
Half-life is about 168 hours, so steady state lands around week 22–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on shortage list: what the trials say vs what this community says in c/compounding · 1 points · 2 months ago
This is correct. The shortage list does expire and the rules change.
comment on the beginner question that gets asked weekly, answered properly in c/newbiequestions · 61 points · 2 months ago
Half-life is about 168 hours, so steady state lands around week 19–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on tried MASH for 15 weeks. here is what happened. in c/survodutide · 12 points · 3 months ago
it is in the wiki actually
comment on tried MASH for 15 weeks. here is what happened. in c/survodutide · 7 points · 3 months ago
Tracking number removed. It identifies both ends of a shipment.
comment on three years of ALT threads, summarised so you do not have to read them in c/bloodwork · 1 points · 3 months ago
What are your reference ranges?
comment on 6 months in and baseline labs is still the thing I get wrong in c/bloodwork · 24 points · 3 months ago
Not to be pedantic but lipids and ApoB are being used interchangeably and they are not interchangeable in real life.
comment on help me understand API source, I have read the wiki twice in c/compounding · 39 points · 3 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on normal: what the trials say vs what this community says in c/newbiequestions · 2 points · 3 months ago
the beginner question is not dumb
comment on [Vendor] QST order #21 — Canada, 21 days, no drama, receipts inside in c/bloodwork · 204 points · 3 months ago
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
comment on [Question] 503A — what am I missing here in c/compounding · 2 points · 3 months ago
regulatory claims need a citation to the actual rule, not interpretation
comment on someone explain first time to me like I have not read a paper in years in c/newbiequestions · 1 points · 4 months ago
Strongly agree. No question is dumb here.
comment on [Question] dose escalation — what am I missing here in c/retatrutide · 0 points · 4 months ago
the glucagon component changes the side effect profile, not just the efficacy
comment on [Question] dose escalation — what am I missing here in c/retatrutide · -21 points · 4 months ago
Strongly agree. Heart rate escalation needs the actual data, not impressions.
comment on bloodwork — my 15-week log, condensed into one table in c/bloodwork · 241 points · 4 months ago
Yeah, baseline matters more than any later number.