u/liver_enzyme_liz
ALT dropped 34 to 19. The fatty-liver story is the underrated one.
member · joined 14 Apr 2024
comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · 143 points · 2 days ago
agreed, and it is in the community rules for exactly that reason. two dual agonists, two completely different second receptors.
comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · 104 points · 2 days ago
on evidentiary quality per participant, biopsy endpoints beat almost everything else in the class. on size, you are right. those are different rankings and i should have said which one i meant.
comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 143 points · 2 days ago
same argument applies to the hepatic side and survodutide. the MASH biopsy endpoints are a different category of evidence to a weight percentage and they get a fraction of the discussion.
comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 39 points · 2 days ago
Disagree. What you are describing is consistent with retatrutide, not with what you concluded.
comment on [PSA] severe abdominal pain is not a forum question in c/sideeffects · 96 points · 3 days ago
and worth saying: normal lipase does not rule out a problem, it rules out one specific problem. people read one normal result as an all-clear.
comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 1 points · 3 days ago
The confident tone is doing a lot of work that the evidence is not.
comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 1 points · 3 days ago
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
comment on [Results] ALT 34 → 19 in seven months, nothing else changed in c/bloodwork · 11 points · 4 days ago
Is that fasted?
comment on [Question] eGFR dropped 8 points during rapid loss, should i worry in c/bloodwork · 7 points · 4 days ago
Flair changed to match the content. Read the sidebar before posting next time and we are square.
comment on [Results] ALT 34 → 19 in seven months, nothing else changed in c/bloodwork · 5 points · 5 days ago
eGFR noise during rapid loss is expected
comment on [Regulatory] state board actions worth reading if you use a compounder in c/compounding · 10 points · 8 days ago
The 503A pharmacy I used lost their shortage list eligibility. Same day, compounding became illegal. Rules are real.
comment on [Results] hs-CRP halved before the scale moved much in c/bloodwork · 204 points · 12 days ago
comment on lipids got worse on paper while everything else got better. triglycerides explain it. in c/bloodwork · 6 points · 18 days ago
ApoB over LDL-C, that is the hierarchy
comment on what is the difference between compounded and the pen in c/newbiequestions · 17 points · 26 days ago
The normal question took me three weeks to understand. Wiki explained it eventually.
comment on week 26 check-in — 31kg down, muscle cramps manageable, one thing confusing me in c/bloodwork · 1 points · 27 days ago
Yeah, baseline matters more than any later number.
comment on what is the difference between compounded and the pen in c/newbiequestions · 13 points · 27 days ago
no dose recommendations for individuals, even here
comment on why do people talk about units and mg like they are different things in c/newbiequestions · 10 points · 1 months ago
rudeness is removed faster than bad questions
comment on TRIUMPH: what the trials say vs what this community says in c/retatrutide · 18 points · 1 months ago
Slight fix: the number was 96.8, not 97.2. Decimal point, but a fairly consequential one.
comment on help me understand A1c, I have read the wiki twice in c/bloodwork · 0 points · 1 months ago
Do you have baseline to compare to?
comment on glucagon is the most under-discussed thing in c/scamalerts in c/survodutide · 13 points · 1 months ago
Mechanistically the bit that matters is glucagon. It explains most of the early profile and a decent chunk of the outcome.