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LI

u/lina_novak

Contributes reviews on supplier material. Based in Porto.

member · joined 11 Feb 2025

3,183post karma
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75comments

comment on [Sceptic] the tendon claims outran the evidence by about a decade in c/bpc157 · 2 points · 2 days ago

Not to be pedantic but sequence and pentadecapeptide are being used interchangeably and they are not interchangeable in real life.

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comment on [Sceptic] the tendon claims outran the evidence by about a decade in c/bpc157 · 2 points · 2 days ago

Slight fix: the number was 98.7, not 98.3. Decimal point, but a fairly consequential one.

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comment on [Method] the gradient everyone uses for sema and why it under-resolves the des-amido in c/hplc · 20 points · 5 days ago

Yeah, the chromatogram profile matters more than the headline number.

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comment on [Caution] research use only. handling questions welcome, protocols are not. in c/bpc157 · 3 points · 6 days ago

handlers in the community are rare and cautious

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comment on [Explainer] integration decisions change your number more than the sample does in c/hplc · 1 points · 6 days ago

chromatogram or it did not happen

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comment on small win: non-peptide stopped being a problem at week 16 in c/orforglipron · 1 points · 16 days ago

This is correct. ATTAIN data is phase 21.

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comment on someone explain chromatogram to me like I have not read a paper in years in c/hplc · 15 points · 1 months ago

Did they post the raw trace or just the summary?

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comment on someone explain chromatogram to me like I have not read a paper in years in c/hplc · 17 points · 1 months ago

two labs, two different baselines, two different purity numbers, both honest

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comment on clothes fit the same for 14 months and it is genuinely strange in c/maintenancephase · 127 points · 1 months ago

the 2.5mg dose works fine for 67 weeks of the month

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comment on [Meta] the small molecule rule is doing its job and people should stop complaining in c/orforglipron · 3 points · 2 months ago

no cold chain means oral GLP-1, if approved

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comment on [Question] rodent data — what am I missing here in c/bpc157 · 23 points · 2 months ago

pentadecapeptide is tendon, the supply chain naming is a mess

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comment on three years of lowest effective dose threads, summarised so you do not have to read them in c/maintenancephase · 1 points · 3 months ago

the lowest dose you can stay on is not the lowest dose that works

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on sequence — my 15-week log, condensed into one table in c/bpc157 · 1 points · 3 months ago

sequence and naming claims need the actual sequence

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comment on sequence — my 15-week log, condensed into one table in c/bpc157 · 2 points · 3 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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comment on the HPLC thing finally clicked for me and I want to write it down in c/hplc · 3 points · 4 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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comment on [Meta] proposal — a flair for small molecule posts in c/orforglipron · 1 points · 4 months ago

the absorption problem is solved by non-peptide structure

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comment on [Meta] proposal — a flair for small molecule posts in c/orforglipron · 91 points · 4 months ago

Yeah, small molecule changes the whole game.

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comment on three years of integration threads, summarised so you do not have to read them in c/hplc · 20 points · 4 months ago

integration decision on a shoulder changes your number by half a point on its own

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comment on France: chromatogram, and what it actually costs here in c/hplc · 9 points · 4 months ago

This is the correct method framing. Column and gradient are load-bearing fields.

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comment on France: chromatogram, and what it actually costs here in c/hplc · 45 points · 4 months ago

the detector wavelength matters more than people think

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Janoshik Analytical

Independent HPLC and mass spec. The number you get is the number they found.

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GL Biochem (Shanghai)

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