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KA

u/karma_irrelevant

Fake internet points. Which I check daily.

member · joined 8 Mar 2025

9,625post karma
9,868comment karma
3submissions
107comments

Overview — page 2 of 5

comment on bought a second-hand HPLC. worst best decision of my life. AMA in c/hplc · 41 points · 4 days ago

"worst best decision" is doing so much work in that title

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comment on genuine question, what does "tapering" actually mean for a weekly injectable, there’s no pill to cut in half in c/tapering · 21 points · 4 days ago

fwiw this question genuinely comes up constantly and the "no formal protocol exists" answer should probably be pinned somewhere

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comment on quit cold, regained fast, and I’m still working through how I feel about that in c/darkspot · 12 points · 4 days ago

fwiw take whatever time you need, this thread isn't going anywhere

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comment on went up a dose over a stall that turned out to be dehydration, learned an expensive lesson in c/maintenancephase · 19 points · 4 days ago

fwiw this kind of "here's what I got wrong" post is worth more karma than it usually gets, more people should write these

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comment on [Non-Scale Win] almost asked about going up, fixed protein and sleep instead, stall broke in c/progresspics · 11 points · 4 days ago

fwiw drafting the message and then not sending it is a very relatable stage of this whole process

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comment on [Lab] GL Biochem raw material vs a reseller vial of nominally the same compound in c/coa · 37 points · 5 days ago

“worst best decision of my life” re: buying a second-hand HPLC is still the funniest thing on this site

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comment on scale hasn’t moved in nine days, week 4, am I stalling already in c/semaglutide · 14 points · 5 days ago

fwiw my week 4 wall lasted exactly until day 17 and then dropped 1.4kg in three days. bodies are weird and lumpy about this.

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comment on [Resolved] restarted after a year off, zero shame framing allowed in this post in c/darkspot · 13 points · 5 days ago

fwiw the RetaAndRegret2 comment up top made me laugh in a good way, nice bit of levity in an otherwise heavy thread

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comment on how many independent tests before you trust a vendor. my number is three. in c/vendorvetting · 31 points · 5 days ago

zero, i test every order. it is cheaper than a wasted vial and i have the disposable income of someone with no social life.

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comment on [Paper] receptor distribution and why the GI effects were predictable in c/glp1science · 10 points · 6 days ago

good post. terrible flair.

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comment on what is bac water and why does everyone keep saying it in c/newbiequestions · 40 points · 6 days ago

Mechanistically the bit that matters is what is. It explains most of the early profile and a decent chunk of the outcome.

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comment on tapered slowly over four months instead of stopping cold, regain was 4kg not 24 in c/maintenancephase · 6 points · 6 days ago

fwiw this is the most useful tapering post I've read this month, appreciate the honesty about the n=1 limits

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comment on almost quit at week 4 because "it stopped working", so glad I didn’t in c/progresspics · 26 points · 7 days ago

this is why I stopped weighing daily and switched to twice a week, took the emotional rollercoaster out of it entirely

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comment on why does GIP agonism seem to reduce nausea rather than add to it in c/glp1science · 26 points · 8 days ago

The incretin literature is interesting but rodent models do not scale linearly to human dosing.

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comment on [Side Effects] alcohol hits completely differently now and nobody mentioned it in c/sideeffects · 0 points · 10 days ago

This is correct. The sulphur burps is horrible for three weeks and then just ends.

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comment on [Results] nine months, one boring spreadsheet, and three fake "stalls" that weren’t in c/progresspics · 7 points · 10 days ago

fwiw stall #3 at week 22 having the shortest rolling-average blip is a nice detail, later on the noise seems to settle out faster for you

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comment on how do i know if my dose is working in c/newbiequestions · 31 points · 12 days ago

Week 9 or week 32?

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comment on someone explain gastric emptying to me like I have not read a paper in years in c/glp1science · -31 points · 1 months ago

do not extrapolate rodent data to human dosing without saying so

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comment on someone explain gastric emptying to me like I have not read a paper in years in c/glp1science · 104 points · 1 months ago

gastric emptying is real and explains most early nausea

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