u/joaquin_stanescu
Contributes reviews on supplier material. Based in Nantes.
member · joined 17 Aug 2025
Comments — page 2 of 5
comment on [Lab] 12th independent test on QSC, and the trend is the interesting part in c/semaglutide · -15 points · 2 months ago
titration speed is titration plus side effects, period
Disagree on that part. 98.7% and 98.9% on the same vial is normal.
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 11 points · 3 months ago
Is that absolute or relative risk reduction?
comment on am I the only one who found titration harder than the injections in c/semaglutide · 58 points · 3 months ago
Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.
comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 58 points · 4 months ago
Is that absolute or relative risk reduction?
comment on [Question] food noise — what am I missing here in c/semaglutide · 1 points · 4 months ago
the quiet is real.
Adding to this: Ozempic is doing more work than the comment implies.
comment on three years of glycaemic control threads, summarised so you do not have to read them in c/t2dglp1 · 25 points · 5 months ago
Has anyone actually got this in writing, or is it forum lore at this point?
comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 40 points · 5 months ago
phase 2 is not phase 3, smaller n and shorter trial
comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 32 points · 5 months ago
You have restated the marketing copy. What is the actual substance here.
comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 1 points · 5 months ago
Yeah, absolute numbers matter more than the press release.
comment on someone explain shipping to me like I have not read a paper in years in c/intlshipping · 39 points · 5 months ago
Australia to Australia: QST with 11 days is the average, variance is 16
comment on someone explain shipping to me like I have not read a paper in years in c/intlshipping · 86 points · 5 months ago
This is correct. Variance is the story.
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 210 points · 5 months ago
dropout handling matters, especially on GI-heavy populations
Yes, exactly this, and it is the bit that took me 10 weeks to accept.
comment on help me understand 2.4mg, I have read the wiki twice in c/semaglutide · 43 points · 5 months ago
New Zealand here. Waited 18 months on an NHS list, gave up, went private, and the cost was half what I expected but the admin was worse.
comment on tried carrier for 22 weeks. here is what happened. in c/intlshipping · 94 points · 5 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on does 2.4mg actually matter or is it forum lore at this point in c/semaglutide · 213 points · 6 months ago
That is net peptide content, not purity. Different number, different meaning.
comment on someone explain Wegovy to me like I have not read a paper in years in c/semaglutide · 242 points · 6 months ago
Slight fix: the number was 98.7, not 98.6. Decimal point, but a fairly consequential one.
comment on week 6 check-in — 47kg down, the food-noise thing manageable, one thing confusing me in c/t2dglp1 · 19 points · 7 months ago
Not convinced. The evidence does not support that reading.
comment on the semaglutide question that gets asked weekly, answered properly in c/semaglutide · 61 points · 7 months ago
Strongly agree. If it is not working at 12.5mg after 31 weeks, going up is not automatically the answer.
comment on tried STEP for 14 weeks. here is what happened. in c/trialwatch · 45 points · 7 months ago
event rates are more informative than hazard ratios alone
comment on three years of transit time threads, summarised so you do not have to read them in c/intlshipping · 1 points · 8 months ago
This is correct. Variance is the story.