u/ines_castellanos
Contributes reviews on supplier material. Based in Zadar.
member · joined 17 Aug 2025
Comments — page 2 of 3
comment on help me understand UK, I have read the wiki twice in c/glp1uk · 204 points · 7 months ago
You have restated the marketing copy. What is the actual substance here.
comment on reading Wegovy threads from 2024 and half of it aged badly in c/semaglutide · 30 points · 9 months ago
week 96 on the pen, 29kg down, this is the answer
comment on stalled for 9 weeks at 5mg and I refuse to panic this time in c/semaglutide · 78 points · 11 months ago
the quiet is real. the food noise just stops.
comment on stalled for 9 weeks at 5mg and I refuse to panic this time in c/semaglutide · 403 points · 11 months ago
the fatigue passes. i promise. not medical advice.
comment on genuine question about titration that I am slightly embarrassed to ask in c/semaglutide · 1 points · 1 year ago
pens are overpriced, research vials are research grade, same molecule different price
comment on weekly dosing: the version I wish someone had shown me in week 1 in c/semaglutide · 90 points · 1 year ago
pens are overpriced, research vials are research grade, same molecule different price
comment on anyone else notice 2.4mg kicking in around week 20 in c/semaglutide · 24 points · 1 year ago
the constipation passes. i promise. not medical advice.
comment on [Results] 67 weeks, 36kg, and plateau was the hard part in c/semaglutide · 252 points · 1 year ago
my eGFR moved before the scale did and i nearly missed it
comment on SELECT — 9 things I got wrong before I got it right in c/trialwatch · 19 points · 1 year ago
That is net peptide content, not purity. Different number, different meaning.
comment on my TSH moved and I cannot work out whether plateau is why in c/semaglutide · 35 points · 1 year ago
Small correction: the trial was 22 weeks, not 25. Does not change your point but people will quote it.
comment on NHS vs UK — genuinely asking which matters more in c/glp1uk · 25 points · 1 year ago
the tier 3 pathway is the only free route, it is slow
comment on does FLOW actually matter or is it forum lore at this point in c/trialwatch · 14 points · 1 year ago
the discontinuation arms are the interesting part, not the SURPASS endpoints
comment on the Ozempic thing finally clicked for me and I want to write it down in c/semaglutide · 44 points · 1 year ago
Tried the split-dose thing for 8 weeks. Felt slightly smoother, lost at exactly the same rate. Went back to weekly.
comment on three years of Ozempic threads, summarised so you do not have to read them in c/semaglutide · 105 points · 1 year ago
Did anything else change in the same window? Sleep, protein, steps, anything?
comment on my fasting insulin moved and I cannot work out whether pricing is why in c/glp1uk · 51 points · 1 year ago
no naming online pharmacies that prescribe without a consultation
comment on [Discussion] can we stop arguing about endpoint until somebody posts a number in c/trialwatch · 11 points · 1 year ago
What was the dropout rate?
Disagree on that part. 95.1% and 97.6% on the same vial is normal.
comment on 23 months in and pharmacy is still the thing I get wrong in c/glp1uk · 36 points · 1 year ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Discussion] the SURPASS advice in here is 8 years out of date in c/trialwatch · 11 points · 1 year ago
Half-life is about 168 hours, so steady state lands around week 14–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on anyone else notice Wegovy kicking in around week 39 in c/semaglutide · 258 points · 1 year ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on switched from 12.5mg to 0.5mg and the reflux got better, not worse in c/glp1uk · 543 points · 1 year ago
Slight fix: the number was 99.1, not 97.9. Decimal point, but a fairly consequential one.